Fosamprenavir (Lexiva) for LPR: An HIV Drug Treats Reflux?

There is a considerable amount of evidence suggesting that pepsin, a common digestive enzyme, is involved in the pathogenesis/pathophysiology of laryngopharyngeal reflux (LPR) disease. (R) Specifically, it is thought that pepsin ends up refluxed into the laryngopharynx from the stomach whereafter it causes damage, inflammation, and dysfunction of the: cells, tissue, mucosal membranes, nerves, and/or …

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Antidepressants Stunt Growth (SSRIs & Height): Future NBAer to Jockey?

Research by Pratt et al. (2017) suggests that 7.8% of individuals between ages 12 and 19 used antidepressants from 2011-2014. (R) Jack et al. (2020) report a continuous rise in the prescribing of antidepressants to adolescents in England; antidepressant prescriptions more than doubled from 2005-2017 among 12-17 year olds. (R) Between April 2015-2021 the number …

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NAC for OCD: An Effective Treatment Option?

NAC has been suggested as a treatment for OCD. It’s likely that NAC can improve OCD symptoms in a subset of persons with OCD – but not everyone. This is because individuals differ in gene expression, brain morphology, neurochemistry, hormones, and general physiology (influencing OCD and reactions to NAC). What is NAC? N-acetylcysteine – or …

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Can Alprazolam (Xanax) Cause Tinnitus & Hearing Loss?

Alprazolam (Xanax) is a benzodiazepine commonly prescribed for the acute treatment of anxiety disorders such as panic disorder and generalized anxiety disorder. From each year between 2004-2019, the number of annual prescriptions for alprazolam in the U.S. ranged between 17-29 million. While alprazolam is regarded as being very effective for the management of anxiety, some …

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Amoxicillin Tinnitus & Hearing Loss: Ototoxic Drug of Concern?

Amoxicillin was discovered in 1958 and used medically in 1972 – and remains among the most commonly prescribed antibiotics due to its low cost and safety profile. It is a moderate-spectrum, bacteriolytic, beta-lactam antibiotic of the aminopenicillin family – prescribed to treat susceptible Gram-positive and Gram-negative bacteria causing: middle ear infection; strep throat; pneumonia; skin …

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Mewing, Orthotropics, Jaw Training: Giga Chad Jawline?

“I started mewing and now I’m a cat.” – Anon. Thoughts on mewing. Wait, you may be asking – WTF is “mewing?” Mewing is a do-it-yourself (DIY) practice – that involves a combination of tongue repositioning and chewing exercises – purported to: (1) reshape aspects of the face (jawline) and (2) mouth (bite & teeth …

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