Can Alprazolam (Xanax) Cause Tinnitus & Hearing Loss?

Alprazolam (Xanax) is a benzodiazepine commonly prescribed for the acute treatment of anxiety disorders such as panic disorder and generalized anxiety disorder. From each year between 2004-2019, the number of annual prescriptions for alprazolam in the U.S. ranged between 17-29 million. While alprazolam is regarded as being very effective for the management of anxiety, some …

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Melatonin & Alprazolam (Xanax) Together: Potent Hypnotic Mix?

Why am I writing about mixing alprazolam (Xanax) and melatonin? Because I’ve done it a few times – and did it last night. My aim was to research whether the combination is safe and/or more useful in certain ways than each substance used individually. Xanax (alprazolam) is a benzodiazepine anxiolytic most commonly used for the …

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Amoxicillin Tinnitus & Hearing Loss: Ototoxic Drug of Concern?

Amoxicillin was discovered in 1958 and used medically in 1972 – and remains among the most commonly prescribed antibiotics due to its low cost and safety profile. It is a moderate-spectrum, bacteriolytic, beta-lactam antibiotic of the aminopenicillin family – prescribed to treat susceptible Gram-positive and Gram-negative bacteria causing: middle ear infection; strep throat; pneumonia; skin …

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Trazodone & Priapism: Earning the Nickname TrazoBONE

Trazodone is a serotonin receptor antagonist and reuptake inhibitor (SARI) that is used primarily for the treatment of major depression. It is also utilized as an off-label treatment for anxiety disorders (e.g. generalized anxiety disorder; panic disorder; PTSD; OCD) and sleep disorders (e.g. insomnia). Although trazodone is an extremely effective drug for various medical conditions …

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Melatonin Shrinks Testicles & Ovaries: Hamster-Sized to Rice Grains?

Earlier this year while listening to podcasts about sleep and insomnia, I stumbled upon the neuroscientist Andrew Huberman of the “Huberman Lab” podcast who discussed melatonin with Matthew Walker (sleep neuroscientist). While discussing melatonin, Huberman stated that he personally avoids it in part due to studies showing that melatonin significantly shrinks testicles and ovaries of …

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Alprazolam (Xanax) for Sleep & Insomnia: Why I Use It Occasionally

Alprazolam (Xanax) is a fast-acting, medium-duration benzodiazepine that was patented in 1971 and approved for medical use in the U.S. in 1981. As of 2019, alprazolam was the 41st most-prescribed medication in the U.S. with over 17M annual prescriptions. It is commonly used for the short-term treatment of anxiety disorders, panic disorder, and generalized anxiety …

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