DREW IS DOPE

stopped working

DrugsFebruary 9, 2022

PPI Stopped Working: Tolerance Onset? Ideas & Solutions

Proton-pump inhibitors (PPIs) are medications that induce profound and prolonged reduction of stomach acid production by irreversibly inhibiting the H+/K+-ATPase proton pump. These medications are utilized as monotherapy or adjunct interventions for the treatm…

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DrugsDecember 1, 2021

Melatonin Stops Working: Causes & Solutions

Melatonin is an endogenous hormone produced by the pineal gland that helps regulate the circadian rhythm. At night, melatonin levels increase (100-300 ng/mL) – and this serves as a physiological signal that it’s time for sleep, and thus we become drowsy/sedate…

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