Alprazolam (Xanax) is a benzodiazepine commonly prescribed for the acute treatment of anxiety disorders such as panic disorder and generalized anxiety disorder. From each year between 2004-2019, the number of annual prescriptions for alprazolam in the U.S. ranged between 17-29 million. While alprazolam is regarded as being very effective for the management of anxiety, some …
Why am I writing about mixing alprazolam (Xanax) and melatonin? Because I’ve done it a few times – and did it last night. My aim was to research whether the combination is safe and/or more useful in certain ways than each substance used individually. Xanax (alprazolam) is a benzodiazepine anxiolytic most commonly used for the …
Alprazolam (Xanax) is a fast-acting, medium-duration benzodiazepine that was patented in 1971 and approved for medical use in the U.S. in 1981. As of 2019, alprazolam was the 41st most-prescribed medication in the U.S. with over 17M annual prescriptions. It is commonly used for the short-term treatment of anxiety disorders, panic disorder, and generalized anxiety …
For the past 1.5 years, I’ve been struggling with intermittent bouts of sleep-maintenance insomnia (i.e. middle insomnia) and terminal insomnia (i.e. early morning awakening insomnia). This causes me to wake up ~2-4 hours before my desired wake time and have difficulty falling back asleep despite feeling mentally and physically tired. It all began ~1-2 months …
Alprazolam is a medium duration-of-action benzodiazepine anxiolytic utilized primarily for the treatment of acute anxiety episodes (e.g. panic attacks). Because alprazolam functions as a positive allosteric modulator (PAM) of GABA-A receptors, it allows endogenous GABA to bind with increased frequency to agonize receptors – which increases CNS inhibition. The combination of: neurochemical modulation AND CNS …