Fosamprenavir (Lexiva) for LPR: An HIV Drug Treats Reflux?

There is a considerable amount of evidence suggesting that pepsin, a common digestive enzyme, is involved in the pathogenesis/pathophysiology of laryngopharyngeal reflux (LPR) disease. (R) Specifically, it is thought that pepsin ends up refluxed into the laryngopharynx from the stomach whereafter it causes damage, inflammation, and dysfunction of the: cells, tissue, mucosal membranes, nerves, and/or …

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Can Reflux Be Cured? (GERD & LPR)

Can reflux diseases be cured? It depends. Sometimes the answer is a resounding “YES” and other times the answer is a probable “NO.” Curability of a reflux condition will vary depending upon 3 factors: 1. Underlying cause(s) of the reflux condition This varies among sufferers. For one person it might be obesity, for another it …

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Stretta Procedure for GERD & LPR: Does It Work?

Stretta is a minimally-invasive procedure that delivers a series of radiofrequency bursts to the gastroesophageal junction (GEJ) to enhance both tone and integrity of the LES via induction of fibrosis and/or hypertrophy. It is thought that enhancement of LES tone and integrity can improve certain chronic reflux conditions such as: GERD (gastroesophageal reflux disease) and …

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