Approximately 10% of the adult population suffers from insomnia, another 20% experiences occasional insomnia symptoms, and it has a 40% persistence rate over a 5-year period. (R) Some effectively manage insomnia with behavioral & lifestyle changes (exercise, zero stimulants, same sleep/wake times, etc.), temperature adjustments (cooler room), cognitive behavioral therapy (CBT), etc. – but for …
Why am I writing about mixing alprazolam (Xanax) and melatonin? Because I’ve done it a few times – and did it last night. My aim was to research whether the combination is safe and/or more useful in certain ways than each substance used individually. Xanax (alprazolam) is a benzodiazepine anxiolytic most commonly used for the …
Alprazolam (Xanax) is a fast-acting, medium-duration benzodiazepine that was patented in 1971 and approved for medical use in the U.S. in 1981. As of 2019, alprazolam was the 41st most-prescribed medication in the U.S. with over 17M annual prescriptions. It is commonly used for the short-term treatment of anxiety disorders, panic disorder, and generalized anxiety …
Diphenhydramine is a first-generation ethanolamine antihistamine developed by George Rieveschl and was approved for usage in 1946. In the U.S. and Canada – diphenhydramine is the primary active ingredient in the over-the-counter medication “Benadryl.” As of 2017, diphenhydramine was the 241st most commonly prescribed medication in the U.S. – exceeding 2M prescriptions. Total usage of …
According to a COVID researcher I follow, approximately 80% of all COVID infections will have lingering/residual symptoms. Most individuals who experience residual COVID symptoms end up making full recovery within 6-12 months – and many others experience partial recovery. Although “fatigue” is the most common symptom after COVID (reported in ~58%) – approximately ~11% experience …