DREW IS DOPE

tolerance

Brain

Melatonin Tolerance: No Evidence It Exists?

Melatonin is a hormone endogenously secreted by the pineal gland at night/evening and regulates one’s circadian rhythm (i.e. sleep-wake cycle) via interaction with melatonin receptors in the brain. Melatonin also: regulates blood pressure; interacts with the i…

Read article
Drugs

Melatonin Stops Working: Causes & Solutions

Melatonin is an endogenous hormone produced by the pineal gland that helps regulate the circadian rhythm. At night, melatonin levels increase (100-300 ng/mL) – and this serves as a physiological signal that it’s time for sleep, and thus we become drowsy/sedate…

Read article