For the past 1.5 years, I’ve been struggling with intermittent bouts of sleep-maintenance insomnia (i.e. middle insomnia) and terminal insomnia (i.e. early morning awakening insomnia). This causes me to wake up ~2-4 hours before my desired wake time and have difficulty falling back asleep despite feeling mentally and physically tired. It all began ~1-2 months …
Doxycycline is a broad-spectrum antibiotic of the “tetracycline” class used to treat a variety of bacterial infections and some parasites. Conditions commonly treated by doxycycline, include: acne; bacterial pneumonia; chlamydia; Lyme disease; cholera; typhus; and syphilis. It is also used to prevent malaria in conjunction with quinine. If you were prescribed doxycycline by a medical …
According to a 2012 survey administered by the American Academy of Sleep Medicine (AASM), around 1.3% of U.S. adults (3.065M) had taken melatonin within the past 30 days. (R) (This was more than a 2-fold increase from just 0.6% of U.S. adults who admitted to using melatonin within the past 30-days in a 2007 survey.) …
Alprazolam is a medium duration-of-action benzodiazepine anxiolytic utilized primarily for the treatment of acute anxiety episodes (e.g. panic attacks). Because alprazolam functions as a positive allosteric modulator (PAM) of GABA-A receptors, it allows endogenous GABA to bind with increased frequency to agonize receptors – which increases CNS inhibition. The combination of: neurochemical modulation AND CNS …
Proton-pump inhibitors (PPIs) are medications that induce profound and prolonged reduction of stomach acid production by irreversibly inhibiting the H+/K+-ATPase proton pump. These medications are utilized as monotherapy or adjunct interventions for the treatment of: gastroesophageal reflux disease (GERD) & laryngopharyngeal reflux (LPR); Barrett’s esophagus; eosinophilic esophagitis; gastritis; gastrinomas; dyspepsia; peptic ulcer; Zollinger-Ellison syndrome; and …
On various websites and forums, there are reports of PPIs (proton-pump inhibitors) causing worse reflux than before using them (i.e. pre-PPI baseline). Additionally, many alternative health practitioners (e.g. naturopaths, chiropractors, etc.) promote the idea that PPIs always worsen reflux – and many people legitimately believe this to be accurate. The truth is that while a …