There is a considerable amount of evidence suggesting that pepsin, a common digestive enzyme, is involved in the pathogenesis/pathophysiology of laryngopharyngeal reflux (LPR) disease. (R) Specifically, it is thought that pepsin ends up refluxed into the laryngopharynx from the stomach whereafter it causes damage, inflammation, and dysfunction of the: cells, tissue, mucosal membranes, nerves, and/or …
Research by Pratt et al. (2017) suggests that 7.8% of individuals between ages 12 and 19 used antidepressants from 2011-2014. (R) Jack et al. (2020) report a continuous rise in the prescribing of antidepressants to adolescents in England; antidepressant prescriptions more than doubled from 2005-2017 among 12-17 year olds. (R) Between April 2015-2021 the number …
NAC has been suggested as a treatment for OCD. It’s likely that NAC can improve OCD symptoms in a subset of persons with OCD – but not everyone. This is because individuals differ in gene expression, brain morphology, neurochemistry, hormones, and general physiology (influencing OCD and reactions to NAC). What is NAC? N-acetylcysteine – or …
Alprazolam (Xanax) is a benzodiazepine commonly prescribed for the acute treatment of anxiety disorders such as panic disorder and generalized anxiety disorder. From each year between 2004-2019, the number of annual prescriptions for alprazolam in the U.S. ranged between 17-29 million. While alprazolam is regarded as being very effective for the management of anxiety, some …
Why am I writing about mixing alprazolam (Xanax) and melatonin? Because I’ve done it a few times – and did it last night. My aim was to research whether the combination is safe and/or more useful in certain ways than each substance used individually. Xanax (alprazolam) is a benzodiazepine anxiolytic most commonly used for the …
Amoxicillin was discovered in 1958 and used medically in 1972 – and remains among the most commonly prescribed antibiotics due to its low cost and safety profile. It is a moderate-spectrum, bacteriolytic, beta-lactam antibiotic of the aminopenicillin family – prescribed to treat susceptible Gram-positive and Gram-negative bacteria causing: middle ear infection; strep throat; pneumonia; skin …