DREW IS DOPE

Research, notes & ideas.

Drugs

PPI Worsening Reflux: Why Does This Happen?

On various websites and forums, there are reports of PPIs (proton-pump inhibitors) causing worse reflux than before using them (i.e. pre-PPI baseline). Additionally, many alternative health practitioners (e.g. naturopaths, chiropractors, etc.) promote the idea…

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Health

MAC Lung & Humidifiers

Many people with MAC lung infection (NTM) wonder whether it’s okay to use a “humidifier” with the condition. Depending on who you ask, you may get vastly different responses. Some think using a humidifier is perfectly fine – as long as certain precautions are…

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Brain

Melatonin Tolerance: No Evidence It Exists?

Melatonin is a hormone endogenously secreted by the pineal gland at night/evening and regulates one’s circadian rhythm (i.e. sleep-wake cycle) via interaction with melatonin receptors in the brain. Melatonin also: regulates blood pressure; interacts with the i…

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Drugs

High Dose Melatonin: Therapeutic or Dangerous?

What is high-dose melatonin? There’s no objective scientific/medical consensus for what is “high-dose” melatonin. You might ask several people what they consider to be a high-dose of melatonin – and you might get entirely different answers. The body endogenous…

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