In 2020, it was estimated that ~9.2% of Americans (around 1 in 10) aged 12+ experienced a major depressive episode within the past year (most common in 18-25 year olds at 17.2% followed by adolescents at 16.9%). (R) Some people effectively manage depression with a combination of behavior & lifestyle modifications (e.g. healthy diet; circadian …
Gabapentin is a commonly-used medication for the treatment of neuropathic pain (e.g. peripheral neuropathy), restless leg syndrome, and seizure prevention & management – as well as other conditions like anxiety disorders & substance use disorders (off-label). Although many find gabapentin effective as a treatment for the aforementioned medical conditions, some are concerned about the drug …
Trazodone is a serotonin receptor antagonist and reuptake inhibitor (SARI) that is used primarily for the treatment of major depression. It is also utilized as an off-label treatment for anxiety disorders (e.g. generalized anxiety disorder; panic disorder; PTSD; OCD) and sleep disorders (e.g. insomnia). Although trazodone is an extremely effective drug for various medical conditions …
Nasopharyngeal reflux (NPR) is a medical diagnosis that is seldom utilized in present day – given the fact that most experts prefer the term “laryngopharyngeal reflux” (LPR) coined by Dr. Jamie Kaufman (MD). In fact, if you search Google for the term “nasopharyngeal reflux” it asks “did you mean laryngopharyngeal reflux?” What is nasopharyngeal reflux …
Alprazolam is a medium duration-of-action benzodiazepine anxiolytic utilized primarily for the treatment of acute anxiety episodes (e.g. panic attacks). Because alprazolam functions as a positive allosteric modulator (PAM) of GABA-A receptors, it allows endogenous GABA to bind with increased frequency to agonize receptors – which increases CNS inhibition. The combination of: neurochemical modulation AND CNS …
What effect does caffeine have on OCD? It likely depends on the specific person with OCD. Not everyone with OCD or a predisposition to OCD will respond identically to caffeine. This is because individuals differ in gene expression, brain morphology, neurochemistry, hormones, and general physiology (influencing OCD and responses to caffeine). Caffeine-gene interactions: ADORA2A: Adenosine …